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GBCC 2025 — Tools

GBCC2025 ran 3 keynotes + 53 oral talks across 5 sessions + 11 lightning talks + 10 hands-on workshops + 50+ posters. A substantial fraction of the oral and lightning talks introduce or update a named Bioconductor package, a Galaxy tool, or a cross-platform integration artifact — that's what this directory captures. Each entry below corresponds to one tool presented at GBCC2025 (Bioconductor package, Galaxy tool, or integration scaffolding).

Status: Active — bulk extraction complete (24 tool entries across Bioconductor packages, Galaxy tools, and cross-platform integration). Talks-with-packages source list at ../program-notes.md. Slide DOIs (Zenodo) and YouTube playlist links TBD pending Bioconductor community deposits.

Per-tool entry template

Each tool gets its own page (tools/<package-slug>.md) following this structure:

# <PackageName>

**One-line description** — what the package does in plain language.

- **Maintainer:** <name> (<institution>)
- **Ecosystem:** Bioconductor / Galaxy / cross-platform
- **Bioconductor:** [package page] *(if applicable)*
- **Galaxy ToolShed:** [tool page] *(if applicable)*
- **Source:** [GitHub link]
- **Vignette / docs:** [link]
- **Status at GBCC2025:** new release / major update / methods talk / case study / workshop / integration demo

## Talk at GBCC2025

- **Speaker:** ...
- **Day / session:** Day X — Oral Session N / Lightning / Workshop
- **Slides:** [Zenodo DOI]
- **Video:** [GBCC2025 YouTube playlist link if recorded]
- **Abstract / talk page:** [scientific-program link or CSHL abstract-book page]

## What it does

2–3 sentences: the problem it solves, key methodological idea, what it consumes/produces.

## Where it fits in the corpus

- AACR 2026: [link if mentioned]
- ISMB 2026: [link if mentioned]
- RECOMB 2026: [link if mentioned]
- Nextflow Summit 2026: [link if mentioned]
- EuroBioC 2025: [link if also presented at sister event]

## Notes

Free-form impressions, benchmarks claimed, comparisons to alternatives. For Galaxy-wrapped Bioconductor tools: link the wrapper PR or the `tools-iuc` shed entry.

Tool index

24 entries from oral sessions, lightning talks, workshops, and the post-conference CoFest deliverable, ordered by day/session. Three keynotes deferred to the keynotes/ subdirectory and day digests.

Skipped (not in this table): community / training / non-tool talks (Doyle on Bioconductor in Africa; Gauthier on UseGalaxy Canada; Santana on sertão research; Kucher on AnVIL training); methods talks without a clearly named package anchor (Hansen on allele-specific methylation; Nanda on viral-infection signaling networks; Lakshman on orthology-at-scale; Eagles on Visium HD; Moses on LUAD spatial; Campillo on differential transcript usage — flagged for follow-up after the abstract book is retrieved).

Package / Tool Ecosystem Domain Speaker Day / Session Slides Video Mentioned elsewhere
GAIA Galaxy AI agent / NLI Qiu, Goecks Day 2 / Oral 1 TBD TBD GalaxyMCP
GalaxyMCP Galaxy AI / MCP Baker, Qiu, Goecks, Schatz Day 2 / Oral 1 TBD TBD GAIA
AnVIL Galaxy + cloud cloud platform Mosher, Schatz et al. Day 2 / Oral 1 + Day 3 workshop TBD TBD bioc-to-galaxy
torch CRAN / R DL / epigenetic clock Jamie Park Day 2 / Oral 2A TBD TBD —
Galaxy-ML2 Galaxy ML tool suite Lyra Junior, Qiu Day 2 / Oral 2A TBD TBD —
NOVA Galaxy neutron scattering Gregory R Watson Day 2 / Oral 2A TBD TBD —
TPV Broker Galaxy scheduler De Geest, Srikakulam et al. Day 2 / Oral 2A TBD TBD —
gINTomics Bioconductor multi-omics integration Velle, Romualdi Day 2 / Oral 2A TBD TBD MOSClip ↗ EuroBioC
RAIDS Bioconductor ancestry inference Belleau, Deschênes et al. Day 2 / Oral 2B TBD TBD —
signifinder Bioconductor cancer signatures Stefania Pirrotta Day 2 / Oral 2B TBD TBD mitology
SEMPLR Bioconductor TF-binding variants Kenney, Boyle, Phanstiel Day 2 / Oral 2B TBD TBD —
Meta-iPep Galaxy metaimmunopeptidomics Do, Mehta Day 2 / Oral 2B TBD TBD —
HiFi-MAG Galaxy long-read metagenomics Collins, Schatz Day 2 / Oral 2B TBD TBD mia
bsseq Bioconductor ASM methylation (ONT) Kasper D Hansen Day 2 / Oral 2B TBD TBD —
SynExtend Bioconductor orthology / ExoLabel Lakshman, Wright Day 2 / Oral 2B TBD TBD —
SeqArray Bioconductor rare-variant annotation Xiuwen Zheng Day 2 / Oral 2B TBD TBD —
Voyager Bioconductor spatial multiscale (LUAD) Lambda Moses Day 2 / Oral 2B TBD TBD SpatialData ↗ EuroBioC
splicelogic Bioconductor differential transcript usage Campillo, Love Day 2 / Oral 2B TBD TBD plyxp
atena Bioconductor transposable elements Robert Castelo Day 3 / Lightning TBD TBD GSVA→Galaxy
iscream Bioconductor BED queries (Rcpp) James Eapen Day 3 / Lightning TBD TBD —
KRSA Bioconductor kinome analysis Ali Imami Day 3 / Lightning TBD TBD —
sosta Bioconductor spatial omics Gunz, Robinson Day 3 / Oral 3 TBD TBD spatialFDA ↗ EuroBioC, SpatialData ↗ EuroBioC
IWC Galaxy workflow registry Marius van den Beek Day 3 / Oral 3 TBD TBD —
spatialLIBD Bioconductor Visium HD Nicholas Eagles Day 3 / Oral 3 TBD TBD Voyager, SpatialData ↗ EuroBioC
mia Bioconductor microbiome Tuomas Borman Day 3 workshop + Day 4 / Oral 5 TBD TBD mia ↗ EuroBioC, miaTime ↗ EuroBioC
Tidyomics Bioconductor tidyverse for omics Stefano Mangiola Day 3 / Lightning + Oral 4 TBD TBD plyxp
bioc-to-galaxy Integration auto-wrap pipeline Joshi, Cumbo, Blankenberg Day 2 + Day 3 workshop TBD TBD GSVA→Galaxy, mia
plyxp Bioconductor dplyr for SummarizedExperiment Landis, Love Day 4 / Oral 5 TBD TBD Tidyomics, DeeDeeExperiment ↗ EuroBioC
mitology Bioconductor mitochondrial activity Pirrotta, Bonora, Calura Day 4 / Oral 5 TBD TBD signifinder
FAIR-EASE Galaxy Earth-system Jossé, Detoc, Bodéré Day 4 / Oral 5 TBD TBD —
ipd CRAN / R post-prediction inference Stephen Salerno Day 2 workshop + Day 4 / Oral 5 TBD TBD —
GSVA→Galaxy Integration wrapper deliverable Cumbo, Joshi, Raubenolt, Blankenberg CoFest (Jun 27-28) — — bioc-to-galaxy, atena

Why this format

  • Cross-vault links matter — same as EuroBioC2025: tool released here, used in cancer-research talk X, benchmarked in methods paper Y, all one click apart
  • Slides + video + vignette + Bioconductor-or-Galaxy page in one place
  • Ecosystem field is GBCC-specific — separates R packages from Galaxy tools from cross-platform scaffolding without forcing them into separate directories
  • Status field distinguishes a v1.0 announcement from a 4-year-old package's annual update from a methods talk from an integration demo
  • Mentioned-elsewhere points the reader at the EuroBioC2025 vault when the same package was presented at both events (Soneson, Mangiola, Castelo, Pirrotta, Borman, and others appear in both lineups)

Open questions for the pilot

  1. Granularity — ✅ inherited from EuroBioC2025: one page per tool
  2. AACR dossier mirroring — ✅ inherited: full entry in both vaults, cross-linked
  3. Sample tools to draft first — open: candidate set is GAIA + GalaxyMCP (Galaxy AI scaffolding pair, exercises the ecosystem-field variant) and RAIDS / signifinder / sosta (canonical Bioconductor methods talks). plyxp is also a strong template-validation pick because it's a tidyverse-for-SummarizedExperiment package — exactly the cross-cutting kind of tool we want to make sure renders well
  4. Edge case: non-Bioconductor tools — open: GBCC's edge case is GAIA / GalaxyMCP / NOVA — Galaxy-side tools with no Bioconductor page at all. Proposed: same template, swap "Bioconductor" line for "Galaxy ToolShed" and use a "Galaxy" ecosystem badge
  5. Galaxy workflows vs. Bioconductor packages — same template, or split? — open: a Galaxy tool/workflow has different surface (XML wrapper, ToolShed entry, training material) than a Bioconductor package (DESCRIPTION, vignette, BiocCheck). The template above tries to unify them with the "Ecosystem" field plus optional Bioconductor/Galaxy-ToolShed lines. Decision deferred until 3 sample entries (1 Bioconductor, 1 Galaxy-only, 1 integration scaffold) are drafted by hand. If the unified shape is awkward, fall back to two templates and add a third for "integration scaffolding" (Bioc-in-Galaxy wrappers, GalaxyMCP-style protocols, automatic-wrapping pipelines).